CLIMARA-50: 12.5 cm2 patch containing 3.8 mg of oestradiol (equivalent to 3.9 mg oestradiol hemihydrate)
CLIMARA-100: 25.0 cm2 patch containing 7.6 mg of oestradiol (equivalent to 7.8 mg oestradiol hemihydrate)
Climara® is indicated for the treatment of moderate-to-severe vasomotor menopausal symptoms, vulval and vaginal atrophy, hypoestrogenism and prevention of osteoporosis. Estrogens should not be used by patients with known or suspected pregnancy, breast cancer, estrogen-dependent neoplasia, undiagnosed abnormal genital bleeding, active thrombophlebitis, or thromboembolic disorders. Estrogens have been reported to increase the risk of endometrial carcinoma. Taking progestins lowers the risk of developing this condition.
Before using
Some medicines or medical conditions may interact with this medicine.
Inform your Doctor or Pharmacist of all prescription and over-the-counter medicine that you are taking. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding.
Use of this medicine is not recommended if you have a history of cancer or pulmonary embolism. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Directions
Follow the directions for using this medicine provided by your doctor.
This medicine comes with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. Remove patch from sachet and peel off liner. Apply to area of clean, dry skin on the buttocks. Do not apply at the waistline. Press firmly in place for 10 seconds. Bathing, swimming, or showering should not affect the patch. Very hot water or steam may loosen it.
If your patch accidently falls off, dry your skin and reapply it.
Store this medicine at room temperature, away from heat and light.
After you remove the used patch, fold the sticky side together. Discard out of the reach of children and pets.
If you forget to change the patch as scheduled, change it as soon as possible and go back to your regular schedule.
Cautions
Do not apply this medicine to skin that is irritated or broken, to skin areas that are exposed to sunlight, or to your breasts.
Do not apply this medicine to the same skin site unless at least 1 week has passed since removal of the patch from that site.
While using this medicine, you may experience absence of menstrual periods. If you experience irregular menstrual periods, contact your doctor.
You should perform regular self-examinations of your breasts. If you have questions about how to do this, ask your doctor, nurse, or pharmacist.
If you have difficulty wearing contact lenses after you begin using this medicine, check with your doctor.
Before taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist.
This medicine may cause dark skin patches on your face. Exposure to the sun may make these patches darker. If patches develop, use a sunscreen or protective clothing when exposed to the sun, sunlamps, or tanning booths.
Do not use this medicine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately.
Possible Side Effects
Side effects, that may go away during treatment, include redness, rash, or skin irritation at the application site; or nausea. If they continue or are bothersome, check with your doctor.
Check with your doctor as soon as possible if you experience
Contact your Doctor immediately if you experience leg pain, chest pain, or sudden shortness of breath.
If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
